Imipenem & Cilastatin Injection 500mg+500mg

Description

Imipenem & Cilastatin Injection

• Product Overview
Imipenem & Cilastatin Injection is a combination carbapenem antibiotic and renal dehydropeptidase inhibitor used for the treatment of severe and complicated bacterial infections caused by susceptible microorganisms. Imipenem provides broad-spectrum antibacterial activity by inhibiting bacterial cell wall synthesis, while Cilastatin inhibits renal dehydropeptidase-I, preventing the degradation of Imipenem in the kidneys and prolonging its therapeutic effect. It is administered by intravenous (IV) infusion or intramuscular (IM) injection and is suitable for adults and children as prescribed by a healthcare professional.

• Available Strength
– Imipenem 500 mg + Cilastatin 500 mg Injection

• Therapeutic Category
Carbapenem Antibiotic + Renal Dehydropeptidase Inhibitor

• Indications
Imipenem & Cilastatin Injection is indicated for the treatment of:
– Complicated Intra-abdominal Infections
– Hospital-Acquired Pneumonia
– Community-Acquired Pneumonia
– Complicated Urinary Tract Infections (UTIs)
– Skin and Soft Tissue Infections
– Bone and Joint Infections
– Septicemia (Bloodstream Infections)
– Gynecological Infections
– Polymicrobial Infections
– Febrile Neutropenia (as part of combination therapy)

• Common Side Effects
Some patients may experience:
– Pain or redness at the injection site
– Nausea
– Vomiting
– Diarrhea
– Headache
– Skin rash
– Elevated liver enzymes

• Serious Side Effects
Seek immediate medical attention if any of the following occur:
– Severe allergic reactions (Anaphylaxis)
– Seizures (especially in patients with CNS disorders or renal impairment)
– Clostridioides difficile-associated diarrhea
– Severe skin reactions
– Blood disorders (thrombocytopenia, leukopenia)
– Kidney impairment

• Precautions
– Use only under the supervision of a healthcare professional.
– For IV infusion or IM injection only.
– Complete the full prescribed course of therapy.
– Use cautiously in patients with allergy to carbapenems, penicillins, or cephalosporins.
– Dose adjustment is required in patients with renal impairment.
– Monitor renal function during prolonged therapy.
– Store below 25°C in a dry place, protected from light.

• Technical Information

• Active Ingredients
– Imipenem – 500 mg
– Cilastatin Sodium – 500 mg

• Mechanism of Action
– Imipenem is a carbapenem antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), resulting in bacterial cell death.
– Cilastatin inhibits renal dehydropeptidase-I, preventing the enzymatic degradation of Imipenem in the kidneys, thereby increasing its effectiveness and duration of action.

• Dosage Form
Sterile Powder for Injection

• Route of Administration
Intravenous (IV) Infusion / Intramuscular (IM) Injection

• Shelf Life
24–36 Months (depending on packaging and regulatory requirements)

• Storage Conditions
Store below 25°C in a dry place, protected from light.

• Product Specifications
Product Name:- Imipenem & Cilastatin Injection
Generic Name:- Imipenem + Cilastatin Sodium
Strength:- 500 mg + 500 mg
Dosage Form:- Sterile Powder for Injection
Category:- Carbapenem Antibiotic + Renal Dehydropeptidase Inhibitor
Packaging:- Glass Vial / Customized Export Packing
Pack Size:- 1 Vial
Shelf Life:- 24–36 Months
Storage:- Below 25°C
Origin:- India

• Regulatory Status & Supply Information
– Manufactured in WHO-GMP compliant facilities.
– Available for international export markets.
– Export documentation support available.
– Private Label Manufacturing available.
– Third-Party Manufacturing available.
– Customized export packaging available.
– Bulk quantities available for distributors, wholesalers, hospitals, and government tenders.

• Who Should Source This Product?
This product is ideal for:
– Pharmaceutical Importers
– Pharmaceutical Distributors
– Medicine Wholesalers
– Hospital Procurement Companies
– Government Procurement Agencies
– Pharmacy Chains
– Tender Suppliers
– Private Label Brands

• Why Source From Mediora Exports?
– Trusted Pharmaceutical Exporter from India
– WHO-GMP Manufacturing Partners
– Competitive International Pricing
– Wide Pharmaceutical Product Portfolio
– Reliable Global Supply Chain
– Flexible Packaging Options
– Timely Delivery
– Complete Export Documentation Support
– Dedicated Export Support Team

• Contact Details
Mediora Exports

📧 Email: info@medioraexports.com

📱 Phone/WhatsApp: +91 99047 64844

For product inquiries, quotations, distributorship opportunities, private labeling, and bulk export orders, please contact our team.